Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Employed in the procedure of multiple myeloma. Its synthesis or analyze is critical for ensuring the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the procedure of prostate most cancers by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound while in the synthesis of imatinib, a drug that targets certain kinds of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is crucial for optimizing the creation process and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat breast cancer, and these intermediates are involved in its generation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist used in the treatment method of breast most cancers. Various intermediates help CAS NO. 302964-08-5 in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the therapy of colorectal cancer and modest mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have numerous programs, like antiviral Attributes.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar amounts.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated N-Pyrazinylcarbonyl-L-phenylalanine with the synthesis of assorted gluconic acid derivatives, that are Employed in meals, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication utilised to control variety two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).